SCHEMBL758577

SCHEMBL758577

COc1ccc(C(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.70
ALDH1A1 P00352 2/20 0.70
RAB9A P51151 2/20 0.68
MAPT P10636 2/20 0.68
NPSR1 Q6W5P4 2/20 0.68
MEN1 O00255 1/20 0.68
MAPK1 P28482 1/20 0.68
KMT2A Q03164 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
HPGD P15428 1/20 0.68
ACHE P22303 1/20 0.65
NPC1 O15118 2/20 0.62
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
GAA P10253 1/20 0.61
TUBB4A P04350 1/20 0.59
TUBB P07437 1/20 0.59
TUBA3C P0DPH7 1/20 0.59
TUBA1B P68363 1/20 0.59
TUBA4A P68366 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15908230 1.00 LMNA (0.70) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL2758528 1.00 LMNA (0.70) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL13220665 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL13862209 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL12341731 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL2604467 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL2614653 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL10014125 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL10093719 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1
SCHEMBL19700986 0.94 LMNA (0.61) LMNAALDH1A1RAB9AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692072-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
US-20250122163-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2025-04-17 US disclosed
EP-4467547-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2024-11-27 EP disclosed
US-20240383894-A1 HETEROBIDENTATE IMIDAZO[1,5-A]PYRIDINE AND IMIDAZO[1,5-A]QUINOLINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME UNIV RUTGERS (US) 2024-11-21 US disclosed
EP-4453822-A1 ENVIRONMENTAL ATTRIBUTES FOR COSMETIC INGREDIENTS BASF SE (DE) 2024-10-30 EP disclosed
EP-4452488-A1 HETEROBIDENTATE IMIDAZO[1,5-A]PYRIDINE AND IMIDAZO[1,5-A]QUINOLINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME Rutgers, The State University Of New Jersey (US) 2024-10-30 EP disclosed
WO-2024202087-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-10-03 WO disclosed
CN-118574818-A Photochromic compound, naphthol derivative, curable composition, optical article, lens and spectacles 株式会社德山 2024-08-30 CN disclosed
US-20240067777-A1 CURABLE COMPOUND PRODUCT DAICEL CORPORATION (JP) 2024-02-29 US disclosed
US-20230374304-A1 THERMOPLASTIC POLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-11-23 US disclosed
EP-0613475-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS. PPG INDUSTRIES INC (US) 1995-02-08 EP disclosed
EP-0613475-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1994-09-07 EP disclosed
WO-1993010112-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1993-05-27 WO disclosed
US-5066818-A Lenses, plastic transparencies PPG INDUSTRIES, INC. (US) 1991-11-19 US disclosed
EP-0426846-A1 FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0074861-B1 AMINOCYCLOPENTANE ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION GLAXO GROUP LIMITED (GB) 1986-08-27 EP disclosed
US-4550142-A UNSATURATED RUBBER MODIFIED WITH AMINOBENZOPHENONE NIPPON ZEON CO. LTD. (JP) 1985-10-29 US disclosed
US-4410521-A ANTICOAGULANTS, BRONCHODILATOR AGENTS GLAXO GROUP LIMITED (GB) 1983-10-18 US disclosed
EP-0074861-A1 Aminocyclopentane esters and their preparation and pharmaceutical formulation GLAXO GROUP LIMITED (GB) 1983-03-23 EP disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122163-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES CCNE1, NAP1L1, CRYZ LMNA 121/4885ALDH1A1 1010/4885RAB9A 3798/4885
US-20240383894-A1 HETEROBIDENTATE IMIDAZO[1,5-A]PYRIDINE AND IMIDAZO[1,5-A]QUINOLINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME NDC1, NUDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 LMNA 2443/4885ALDH1A1 2572/4885RAB9A 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.