Prosulfuron

Prosulfuron

SCHEMBL7585855

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(F)(F)F)n1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
THRB P10828 1/20 0.34
VDR P11473 1/20 0.34
TBXA2R P21731 4/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
MAPT P10636 2/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31
CCR6 P51684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prosulfuron SCHEMBL7576349 0.95 TDP1 (0.39) TDP1MEN1KMT2ATTRPPOX
Prosulfuron SCHEMBL7585404 0.93 TDP1 (0.37) TDP1MEN1KMT2ATTRPPOX
Primisulfuron SCHEMBL7580830 0.92 TDP1 (0.39) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7584079 0.92 TDP1 (0.40) TDP1MEN1KMT2ATTRPPOX
Rimsulfuron SCHEMBL7577996 0.92 TDP1 (0.35) TDP1MEN1KMT2ATTRPPOX
Prosulfuron SCHEMBL7581809 0.92 TDP1 (0.36) TDP1MEN1KMT2ATTRPPOX
Prosulfuron SCHEMBL7586681 0.92 TDP1 (0.36) TDP1MEN1KMT2ATTRPPOX
Prosulfuron SCHEMBL7581529 0.92 KMT2A (0.36) TDP1MEN1KMT2ATTRPPOX
SCHEMBL7580028 0.91 TDP1 (0.47) TDP1MEN1KMT2ATTRPPOX
Prosulfuron SCHEMBL7585857 0.91 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.