⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7035031 | 0.97 | — | — | |
| Propanol SCHEMBL7592336 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL48646 | 0.84 | — | — | |
| SCHEMBL3423317 | 0.81 | — | — | |
| SCHEMBL11146467 | 0.81 | CA2 (0.39) | — | |
| SCHEMBL8463463 | 0.81 | CA2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL8643543 | 0.81 | UBE2N (0.42) | — | |
| SCHEMBL9693141 | 0.81 | CA2 (0.44) | — | |
| SCHEMBL9821164 | 0.81 | CASP2 (0.44) | — | |
| SCHEMBL347724 | 0.81 | CASP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147498-C | Method for preparing oxazaphosphorin-2-amines | ASTAҩ��ɷݹ�˾ | 2004-04-28 | — | — | CN | claimed |
| EP-1012152-B1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | BAXTER HEALTHCARE SA (CH) | 2002-10-09 | — | — | EP | claimed |
| CN-1268950-A | Method for preparing oxazaphosphorin-2-amines | ASTA MEDICA AG (DE) | 2000-10-04 | — | — | CN | claimed |
| EP-1012152-A1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | ASTA Medica Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | claimed |
| WO-1999012942-A1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | claimed |
| EP-2760860-B1 | NITROGEN MUSTARD DERIVATIVES | EURO CELTIQUE SA (LU) | 2016-11-16 | — | — | EP | disclosed |
| CN-1147498-C | Method for preparing oxazaphosphorin-2-amines | ASTAҩ��ɷݹ�˾ | 2004-04-28 | — | — | CN | disclosed |
| EP-1012152-B1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | BAXTER HEALTHCARE SA (CH) | 2002-10-09 | — | — | EP | disclosed |
| CN-1268950-A | Method for preparing oxazaphosphorin-2-amines | ASTA MEDICA AG (DE) | 2000-10-04 | — | — | CN | disclosed |
| EP-1012152-A1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | ASTA Medica Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999012942-A1 | METHOD FOR PREPARING OXAZAPHOSPHORIN-2-AMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| EP-0295576-B1 | PROCESS FOR THE PRODUCTION OF THE DERIVATIVES OF 1,3,2-OXAZAPHOSPHORINANE | INSTYTUT PRZEMYSLU FARMACEUTYCZNEGO (PL) | 1993-05-19 | — | — | EP | disclosed |
| US-4908464-A | Process for the production of 1,3,2-oxazaphosphorinanes | INSTYTUT PRZEMYSLU FARMACEUTYCZNEGO (PL) | 1990-03-13 | — | — | US | disclosed |