Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177808 | 0.85 | PTGER2 (0.58) | PTGER2PTGER3HTTPTGER4PTGIR | |
| SCHEMBL7593540 | 0.84 | TRPA1 (0.55) | PTGER2PTGER3PTGIRHPGD | |
| SCHEMBL7582636 | 0.84 | PTGER2 (0.46) | PTGER2PTGER3PTGER4PTGIRNR1I2 | |
| SCHEMBL7585988 | 0.78 | PTGER2 (0.57) | PTGER2PTGER3PTGER4PTGIR | |
| SCHEMBL7588668 | 0.77 | PTGER2 (0.49) | PTGER2PTGER3PTGER4PTGIRHPGD | |
| SCHEMBL7590855 | 0.77 | PTGER2 (0.49) | PTGER2PTGER3PTGER4PTGIRHPGD | |
| SCHEMBL8090822 | 0.76 | PTGER2 (0.54) | PTGER2PTGER3PTGER4PTGIRTBXA2R | |
| SCHEMBL7601951 | 0.75 | PTGER2 (0.44) | PTGER2PTGER3HTTPTGER4PTGIR | |
| SCHEMBL7584569 | 0.75 | PTGER2 (0.43) | PTGER2PTGER3PTGER4PTGIRPTGER1 | |
| SCHEMBL7591974 | 0.75 | PTGER2 (0.43) | PTGER2PTGER3PTGER4PTGIRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |