Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.44 |
| ▸ | PTGIR | P43119 | 4/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591263 | 0.91 | PTGER3 (0.34) | PTGER2PTGER3 | |
| SCHEMBL7177850 | 0.86 | PTGER3 (0.32) | PTGER2PTGER3 | |
| SCHEMBL7582636 | 0.84 | PTGER2 (0.46) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7172727 | 0.76 | PTGER2 (0.57) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7584898 | 0.76 | PTGER2 (0.57) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7584493 | 0.75 | PTGER2 (0.45) | PTGER2PTGER3PTGIRPTGER4 | |
| SCHEMBL7585974 | 0.75 | PTGER2 (0.52) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7593540 | 0.73 | TRPA1 (0.55) | PTGER2PTGER3PTGIRHPGD | |
| SCHEMBL7200047 | 0.73 | PTGIR (0.36) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7590855 | 0.72 | PTGER2 (0.49) | PTGER2PTGER3PTGIRPTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |