Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8018024 | 0.99 | OPRK1 (0.43) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL7588566 | 0.90 | G6PC1 (0.41) | OPRK1OPRM1OPRD1ESR1 | |
| Hydrochloric Acid SCHEMBL8017509 | 0.89 | G6PC1 (0.41) | OPRK1OPRM1OPRD1ESR1 | |
| SCHEMBL7584182 | 0.85 | ESR1 (0.40) | OPRK1OPRD1ESR1 | |
| SCHEMBL7591956 | 0.85 | CYP2D6 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8011601 | 0.84 | ESR1 (0.39) | OPRK1OPRD1ESR1 | |
| Hydrochloric Acid SCHEMBL8014130 | 0.84 | CYP2D6 (0.44) | — | |
| SCHEMBL7587127 | 0.83 | CHRNB4 (0.40) | OPRK1OPRD1DRD2ESR1 | |
| SCHEMBL7587120 | 0.83 | CHRNB4 (0.40) | OPRK1OPRD1DRD2ESR1 | |
| SCHEMBL7606326 | 0.82 | BCHE (0.42) | OPRK1OPRM1OPRD1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864559-B1 | Substituted amino compounds and their use as analgesic active substances | GRUENENTHAL GMBH (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0864559-A1 | Substituted amino compounds and their use as analgesic active substances | Grünenthal GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |