Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962214 | 0.87 | LMNA (0.53) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL2010436 | 0.87 | LMNA (0.59) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL23022578 | 0.87 | CYP3A4 (0.53) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16950574 | 0.86 | ELANE (0.43) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16962213 | 0.86 | LMNA (0.40) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL8897429 | 0.84 | MAPT (0.56) | LMNAMAPTMEN1KMT2AELANE | |
| SCHEMBL16954804 | 0.82 | LMNA (0.49) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16954806 | 0.82 | CYP4F2 (0.65) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16961867 | 0.81 | LMNA (0.37) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16961868 | 0.81 | LMNA (0.47) | LMNAMAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094942-C | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-11-27 | — | — | CN | disclosed |
| EP-0850948-B1 | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-6048842-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| CN-1190097-A | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO (JP) | 1998-08-12 | — | — | CN | disclosed |
| EP-0850948-A1 | Propiophenone derivatives and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |