Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435530 | 0.86 | MAPT (0.68) | MAPTTDP1ELANEKMT2AMEN1 | |
| SCHEMBL16705193 | 0.84 | ELANE (0.75) | MAPTTDP1ELANEKMT2AMEN1 | |
| SCHEMBL2755026 | 0.84 | KMT2A (0.68) | MAPTTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7586397 | 0.84 | LMNA (0.50) | MAPTELANEKMT2AMEN1MAPK1 | |
| SCHEMBL10959120 | 0.83 | MAPT (0.63) | MAPTTDP1ELANEKMT2AMEN1 | |
| SCHEMBL16429669 | 0.82 | ELANE (0.79) | MAPTTDP1ELANEKMT2AMEN1 | |
| Acetic Acid Phenyl Ester SCHEMBL5189342 | 0.82 | MAPT (0.67) | MAPTTDP1ELANEKMT2AMEN1 | |
| SCHEMBL9356185 | 0.81 | ELANE (0.56) | MAPTTDP1ELANEKMT2AMEN1 | |
| SCHEMBL28703613 | 0.79 | KMT2A (0.54) | MAPTTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL16429666 | 0.79 | ELANE (0.72) | MAPTTDP1ELANEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712493-A4 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMA CORP (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0712493-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004277-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |