SCHEMBL7586456

SCHEMBL7586456

C/C=C/[C@@H]1[C@@H](C(=O)O)C1(C)C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
APLNR P35414 1/20 0.31
UGT2B7 P16662 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419338 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419331 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7228981 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL115744 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419340 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4992477 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL215525 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7586461 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419335 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7228985 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939073-B1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2002-12-04 EP disclosed
US-6225495-B1 PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-01 US disclosed
EP-0939073-A1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-01 EP disclosed