SCHEMBL215525

SCHEMBL215525

C/C=C\C1C(C(=O)O)C1(C)C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
APLNR P35414 1/20 0.31
UGT2B7 P16662 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419338 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419331 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7228981 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7586456 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL115744 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419340 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4992477 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7586461 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL4419335 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1
SCHEMBL7228985 1.00 LMNA (0.32) LMNAALDH1A1TP53ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113348161-B Method for producing ester compound 住友化学株式会社 2023-11-28 CN claimed
EP-3014994-B1 MICROCAPSULES FOR THERMAL TRANSPIRATION SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP claimed
EP-2670246-B1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL CO (JP) 2017-10-04 EP claimed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP claimed
EP-1681282-B1 METHOD FOR PRODUCING 3,3-DIMETHYL-2-(1-PROPENYL) CYCLOPROPANE CARBOXYLATE SUMITOMO CHEMICAL CO (JP) 2013-01-23 EP claimed
EP-2034840-B1 PESTICIDAL COMPOSITION COMPRISING TETRAFLUOROBENZYL CYCLOPROPANE CARBOXYLATES SUMITOMO CHEMICAL CO (JP) 2011-06-01 EP claimed
US-7741511-B2 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US claimed
EP-1563735-B1 Fabric protectant SUMITOMO CHEMICAL CO (JP) 2009-11-18 EP claimed
US-7393971-B2 Method for producing 3,3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-01 US claimed
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS SOUDA HIROSHI 2008-01-10 US claimed
US-20030032839-A1 Process for racemizing optically active vinyl-substituted cyclopropanecarboxylic acid compound PANASONIC CORPORATION (JP) 2003-02-13 US claimed
EP-0992479-B1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2003-01-02 EP claimed
EP-0939073-B1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2002-12-04 EP claimed
US-6441220-B1 ESTERIFICATION WITH ALCOHOL IN PRESENCE OF BASIC CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-27 US claimed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP claimed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US claimed
EP-1061065-A2 Methods for producing cyclopropane carboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-20 EP claimed
US-6072074-A Process for producing 3-propynyl-2-2-dimethylcycloprophane-carboxylic acid and its lower akyl esters SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-06-06 US claimed
EP-0992479-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-12 EP claimed
EP-0955287-A1 Propynyl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 LMNA 1815/4885ALDH1A1 671/4885TP53 4589/4885
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS ACSL6, ALKBH3, ACSL1 LMNA 3667/4885ALDH1A1 184/4885TP53 3860/4885
US-20030032839-A1 Process for racemizing optically active vinyl-substituted cyclopropanecarboxylic acid compound NOS1, CYP1B1, CBR1 LMNA 2790/4885ALDH1A1 258/4885TP53 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.