Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30561151 | 1.00 | OPRM1 (0.47) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL29442961 | 0.98 | OPRM1 (0.45) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL29793967 | 0.97 | OPRM1 (0.45) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL497331 | 0.90 | FKBP4 (0.43) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL5704652 | 0.88 | FKBP4 (0.48) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL6049428 | 0.88 | NTSR2 (0.48) | OPRM1OPRD1NPFFR1NPFFR2 | |
| SCHEMBL6058133 | 0.88 | OPRM1 (0.56) | OPRM1OPRD1OPRK1TACR1FKBP4 | |
| SCHEMBL30831830 | 0.88 | F2 (0.59) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| Acetic Acid SCHEMBL3281925 | 0.88 | FKBP4 (0.48) | OPRM1OPRD1OPRK1TACR1FKBP4 | |
| Hydrochloric Acid SCHEMBL7752557 | 0.88 | FKBP4 (0.48) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100337-A2 | ANTITHROMBOTIC THROMBIN VARIANTS | EMORY UNIVERSITY (US) | 2002-12-19 | — | — | WO | disclosed |
| US-4217269-A | FOR SPECTROPHOTOMETRIC MEASUREMENT OF PROTEOLYTIC ENZYMES | ABBOTT LABORATORIES (US) | 1980-08-12 | — | — | US | disclosed |