Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP4 | Q02790 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7752557 | 0.99 | FKBP4 (0.48) | FKBP4TACR1OPRM1OPRK1SSTR3 | |
| Acetic Acid SCHEMBL3281925 | 0.98 | FKBP4 (0.48) | FKBP4TACR1OPRM1OPRK1SSTR3 | |
| SCHEMBL27635235 | 0.89 | OPRM1 (0.46) | FKBP4TACR1OPRM1OPRK1OPRD1 | |
| 4-Nitroaniline SCHEMBL27635238 | 0.89 | OPRM1 (0.46) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7586649 | 0.88 | OPRM1 (0.47) | FKBP4TACR1OPRM1OPRK1NPFFR1 | |
| SCHEMBL30561151 | 0.88 | OPRM1 (0.47) | FKBP4TACR1OPRM1OPRK1NPFFR1 | |
| SCHEMBL11600367 | 0.86 | F2 (0.51) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8529458 | 0.86 | F2 (0.51) | OPRM1OPRK1OPRD1 | |
| SCHEMBL29442961 | 0.86 | OPRM1 (0.45) | FKBP4TACR1OPRM1OPRK1NPFFR1 | |
| Hydrochloric Acid SCHEMBL29793967 | 0.86 | OPRM1 (0.45) | FKBP4TACR1OPRM1OPRK1NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630139-B2 | Expression and purification of recombinant proteins from snake venom | ACADEMIA SINICA (TW) | 2003-10-07 | — | — | US | claimed |
| US-20030039644-A1 | Fibrinogenolytic proteases with thrombolytic and antihypertensive activities: medical application and novel process of expression and production | ACADEMIA SINICA | 2003-02-27 | — | — | US | claimed |
| EP-1196579-B1 | TRYPTASE INHIBITOR | EVOLUTEC LTD (GB) | 2006-09-13 | — | — | EP | disclosed |
| US-6987168-B1 | Tryptase inhibitor proteins derived from blood-feeding anthropod ectoparasites | EVOLUTEC LIMITED (GB) | 2006-01-17 | — | — | US | disclosed |
| US-20040266995-A1 | Fibrinogenolytic proteases with thrombolytic and antihypertensive activities from Taiwan habu: medical application and novel process of expression and production | ACADEMIA SINICA | 2004-12-30 | — | — | US | disclosed |
| US-6630139-B2 | Expression and purification of recombinant proteins from snake venom | ACADEMIA SINICA (TW) | 2003-10-07 | — | — | US | disclosed |
| US-20030114372-A1 | Protease inhibitor peptides | WHITE R TYLER (US) | 2003-06-19 | — | — | US | disclosed |
| US-20030039644-A1 | Fibrinogenolytic proteases with thrombolytic and antihypertensive activities: medical application and novel process of expression and production | ACADEMIA SINICA | 2003-02-27 | — | — | US | disclosed |
| US-20030017546-A1 | PROTEASE INHIBITOR PEPTIDES | SCIOS, INC. | 2003-01-23 | — | — | US | disclosed |
| EP-1196579-A2 | TRYPTASE INHIBITOR | Evolutec Ltd. (GB) | 2002-04-17 | — | — | EP | disclosed |
| US-20010020003-A1 | PROTEASE INHIBITOR PEPTIDES | WHITE R TYLER (US) | 2001-09-06 | — | — | US | disclosed |
| WO-2001005823-A2 | TRYPTASE INHIBITOR | EVOLUTEC LTD. (GB) | 2001-01-25 | — | — | WO | disclosed |
| EP-1067961-A2 | LEISHMANIA CYSTEINE PROTEINASES | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999063090-A2 | PROTEASE INHIBITOR PEPTIDES | SCIOS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| US-5968782-A | NUCLEIC ACID SEQUENCE CODING POLYPEPTIDE ENZYME WITH ENTEROKINASE SENSITIVITY WHICH CAN BE USED FOR TREATING DISORDERS MEDIATED BY THROMBUS CLOT FORMATION | BRIGHAM AND WOMENS'S HOSPITAL, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1999051264-A2 | LEISHMANIA CYSTEINE PROTEINASES | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 1999-10-14 | — | — | WO | disclosed |
| US-5962266-A | DNA WHICH CODES FOR KALLIKREIN INHIBITOR; FOR REDUCING PULMONARY DAMAGE OR BLOOD LOSS DURING CARDIOPULMONARY BYPASS SURGERY | SCIOS, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| US-5955431-A | POLYPEPTIDES AS ANTIINFLAMMATORY AGENTS | BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| WO-1998033812-A1 | MAST CELL PROTEASE PEPTIDE INHIBITORS | BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998024886-A1 | MAST CELL PROTEASE THAT CLEAVES FIBRINOGEN | BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 1998-06-11 | — | — | WO | disclosed |