Lactofen

Lactofen

SCHEMBL7586904

CC1(C)OC(c2ccco2)CN1C(=O)C(Cl)Cl.CCOC(=O)C(C)OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCc1cccc(CC)c1N(COC)C(=O)CCl

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
PPOX P50336 1/20 0.36
KMT2A Q03164 1/20 0.36
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7585292 0.94 TDP1 (0.35) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7577779 0.94 MEN1 (0.33) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7580931 0.93 MEN1 (0.33) TDP1MEN1TTRPPOXKMT2A
Alachlor SCHEMBL7578672 0.93 TDP1 (0.37) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7577502 0.92 TDP1 (0.45) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7576121 0.92 MEN1 (0.32) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7588259 0.91 MEN1 (0.35) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7577624 0.90 MEN1 (0.36) TDP1MEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7585060 0.90 MEN1 (0.37) TDP1MEN1TTRPPOXKMT2A
Alachlor SCHEMBL7589938 0.89 TP53 (0.33) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.