Prosulfuron

Prosulfuron

SCHEMBL7587084

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(F)(F)F)n1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
JMJD7 P0C870 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
CCR6 P51684 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TBXA2R P21731 3/20 0.31
TTR P02766 1/20 0.31
PPOX P50336 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorsulfuron SCHEMBL7590471 0.92 TDP1 (0.45) TDP1JMJD7KMT2AMEN1LMNA
Prosulfuron SCHEMBL7576380 0.92 KMT2A (0.42) TDP1KMT2AMEN1LMNAMAPT
Bifenox SCHEMBL7583229 0.91 TDP1 (0.44) TDP1JMJD7KMT2AMEN1LMNA
Prosulfuron SCHEMBL7581529 0.90 KMT2A (0.36) TDP1KMT2AMEN1LMNAMAPT
Prosulfuron SCHEMBL7579908 0.90 TDP1 (0.50) TDP1KMT2AMEN1LMNANPC1
Prosulfuron SCHEMBL7578937 0.90 KMT2A (0.37) TDP1KMT2AMEN1LMNAMAPT
Lactofen SCHEMBL7588452 0.90 KMT2A (0.35) TDP1KMT2AMEN1LMNAMAPT
Logran SCHEMBL7575531 0.89 TDP1 (0.42) TDP1JMJD7KMT2AMEN1LMNA
Prosulfuron SCHEMBL7579373 0.89 KMT2A (0.34) TDP1KMT2AMEN1LMNAMAPT
Bifenox SCHEMBL7580062 0.87 TDP1 (0.42) TDP1JMJD7KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885JMJD7 789/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.