Pyrazon

Pyrazon

SCHEMBL7587115

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].Nc1cnn(-c2ccccc2)c(=O)c1Cl

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 2/20 0.51
TTR P02766 1/20 0.51
PPOX P50336 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.36
NPBWR1 P48145 4/20 0.36
MCHR1 Q99705 4/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 3/20 0.35
FFAR1 O14842 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.34
VDR P11473 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7583190 0.90 MEN1 (0.49) KMT2ATDP1MEN1TTRPPOX
Acifluorfen SCHEMBL7578149 0.88 TDP1 (0.67) KMT2ATDP1MEN1TTRPPOX
Oxyfluorfen SCHEMBL7581479 0.85 MEN1 (0.47) KMT2ATDP1MEN1TTRPPOX
SCHEMBL7586912 0.84 TDP1 (0.53) KMT2ATDP1MEN1TTRPPOX
SCHEMBL38860 0.84 MEN1 (0.68) KMT2ATDP1MEN1TTRPPOX
Aclonifen SCHEMBL7580224 0.84 TDP1 (0.58) KMT2ATDP1MEN1TTRPPOX
Fomesafen SCHEMBL7582939 0.84 TDP1 (0.53) KMT2ATDP1MEN1TTRPPOX
SCHEMBL10536730 0.83 MEN1 (0.67) KMT2ATDP1MEN1TTRPPOX
SCHEMBL8534878 0.82 MEN1 (0.66) KMT2ATDP1MEN1TTRPPOX
Acifluorfen SCHEMBL7578255 0.82 TDP1 (0.75) KMT2ATDP1MEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885TDP1 1969/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.