Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Threonine SCHEMBL7587327 | 1.00 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| Valine SCHEMBL9779769 | 0.88 | SLC1A1 (0.58) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| Threonine SCHEMBL29102361 | 0.83 | SLC1A3 (0.50) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL724210 | 0.82 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL8232952 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL17878731 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL14908325 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL216743 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL12053128 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL216744 | 0.81 | ALDH1A1 (0.55) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363436-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2024-05-08 | — | — | EP | claimed |
| CN-117940444-A | Caspase-2 inhibitor compounds | 金特速吉医疗有限责任公司 | 2024-04-26 | — | — | CN | claimed |
| WO-2023275357-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-05 | — | — | WO | claimed |
| EP-4112631-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-04 | — | — | EP | claimed |
| EP-4363436-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2024-05-08 | — | — | EP | disclosed |
| CN-117940444-A | Caspase-2 inhibitor compounds | 金特速吉医疗有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023275357-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-05 | — | — | WO | disclosed |
| EP-4112631-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-04 | — | — | EP | disclosed |
| WO-2002100885-A2 | A PENTA- OR TETRAPEPTIDE BINDING TO SOMATOSTATIN RECEPTORS AND THE USE OF THE SAME | NOVASPIN BIOTECH GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |