SCHEMBL758741

SCHEMBL758741

COCCCCOC(=O)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.81
LMNA P02545 3/20 0.65
TSHR P16473 6/20 0.56
MAPK1 P28482 3/20 0.52
HIF1A Q16665 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KMT2A Q03164 1/20 0.52
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
POLB P06746 1/20 0.51
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
ESR1 P03372 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13881856 0.98 TDP1 (0.79) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL9952023 0.96 TDP1 (0.75) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL29319784 0.93 TDP1 (0.71) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL223441 0.90 TDP1 (1.00) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL13291922 0.90 TDP1 (0.66) TDP1LMNATSHRMAPK1KMT2A
Formic Acid SCHEMBL28314231 0.90 TDP1 (0.66) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL514995 0.89 TSHR (0.69) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL2069111 0.88 TDP1 (0.96) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL17466182 0.88 TDP1 (0.96) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL11896606 0.88 TDP1 (0.96) TDP1LMNATSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778442-A Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-11 CN claimed
CN-112759683-A Olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-116135892-B Method for preparing bimodal polyethylene resin for pipe material and bimodal polyethylene resin thereof 中国石油化工股份有限公司 2024-10-15 CN disclosed
CN-117003915-A Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2023-11-07 CN disclosed
CN-116135892-A Method for preparing bimodal polyethylene resin for pipe material and bimodal polyethylene resin thereof 中国石油化工股份有限公司 2023-05-19 CN disclosed
CN-111057169-B Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2023-02-28 CN disclosed
CN-111057168-B Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2022-07-12 CN disclosed
CN-112778442-A Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-11 CN disclosed
CN-112759683-A Olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-07 CN disclosed
CN-111057169-A Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
CN-111057168-A Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
US-8138231-B2 Polymer having oxycarbon group, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
US-7524562-B2 Method of improving abrasion resistance of plastic article using functionalized polymers and article produced thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-28 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-20070085242-A1 Method of improving abrasion resistance of plastic article using functionalized polymers and article produced thereby GENERAL ELECTRIC COMPANY (US) 2007-04-19 US disclosed