SCHEMBL9952023

SCHEMBL9952023

COCCCOC(=O)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.75
LMNA P02545 2/20 0.65
TSHR P16473 4/20 0.56
MAPK1 P28482 2/20 0.52
HIF1A Q16665 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KMT2A Q03164 1/20 0.52
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 1/20 0.50
ESR1 P03372 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
NR1H2 P55055 1/20 0.50
RNASEL Q05823 1/20 0.50
SCN1A P35498 1/20 0.49
SCN2A Q99250 1/20 0.49
SCN3A Q9NY46 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758741 0.96 TDP1 (0.81) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL13881856 0.95 TDP1 (0.79) TDP1LMNATSHRMAPK1HIF1A
Formic Acid SCHEMBL28314231 0.93 TDP1 (0.66) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL29319784 0.93 TDP1 (0.71) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL416566 0.90 TDP1 (0.91) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL514995 0.89 TSHR (0.69) TDP1LMNATSHRMAPK1HIF1A
Hydrochloric Acid SCHEMBL28478926 0.87 TSHR (0.67) TDP1LMNATSHRMAPK1HIF1A
Ammonia Solution, Strong SCHEMBL27732716 0.87 TSHR (0.67) TDP1LMNATSHRMAPK1HIF1A
SCHEMBL13291922 0.86 TDP1 (0.66) TDP1LMNATSHRMAPK1KMT2A
SCHEMBL223441 0.86 TDP1 (1.00) TDP1LMNATSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778442-A Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-11 CN claimed
CN-112759683-A Olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-116135892-B Method for preparing bimodal polyethylene resin for pipe material and bimodal polyethylene resin thereof 中国石油化工股份有限公司 2024-10-15 CN disclosed
CN-117003915-A Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2023-11-07 CN disclosed
CN-116135892-A Method for preparing bimodal polyethylene resin for pipe material and bimodal polyethylene resin thereof 中国石油化工股份有限公司 2023-05-19 CN disclosed
CN-111057169-B Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2023-02-28 CN disclosed
CN-111057168-B Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2022-07-12 CN disclosed
CN-112778442-A Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-11 CN disclosed
CN-112759683-A Olefin polymerization catalyst and application 中国石油化工股份有限公司 2021-05-07 CN disclosed
EP-3694856-A1 FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE Sunshine Lake Pharma Co., Ltd. (CN) 2020-08-19 EP disclosed
CN-111057168-A Catalyst for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
EP-3478663-A1 LACTAM-FUNCTIONALIZED POLYMER, COMPOSITIONS AND APPLICATIONS THEREOF Hercules LLC (US) 2019-05-08 EP disclosed
WO-2019063748-A1 ROR-GAMMA INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-04-04 WO disclosed
WO-2018219356-A1 FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-12-06 WO disclosed
WO-2018005731-A1 LACTAM-FUNCTIONALIZED POLYMER, COMPOSITIONS AND APPLICATIONS THEREOF HERCULES LLC (US) 2018-01-04 WO disclosed
CN-104822678-B Compound with muscarinic receptor antagonist and beta 2-adrenergic receptor agonists activity 奇斯药制品公司 2017-03-08 CN disclosed
EP-2655426-A1 CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME Dow Global Technologies LLC (US) 2013-10-30 EP disclosed
EP-2655425-A1 PROCESS FOR PRODUCING PROCATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND PRODUCT Dow Global Technologies LLC (US) 2013-10-30 EP disclosed
WO-2012087531-A1 CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
WO-2012087527-A1 PROCESS FOR PRODUCING PROCATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND PRODUCT DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed