Sulcotrione

Sulcotrione

SCHEMBL7587501

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1.C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
HPD P32754 1/20 0.37
THRB P10828 1/20 0.34
VDR P11473 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
FFAR1 O14842 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesotrione SCHEMBL7579020 0.97 TDP1 (0.41) TDP1MEN1KMT2ATTRPPOX
Sulcotrione SCHEMBL7578268 0.95 MEN1 (0.43) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7578196 0.92 TDP1 (0.40) TDP1MEN1KMT2ATTRPPOX
Mesotrione SCHEMBL7589216 0.92 MEN1 (0.43) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7579292 0.91 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX
Oxyfluorfen SCHEMBL7579249 0.90 MEN1 (0.41) TDP1MEN1KMT2ATTRPPOX
Sulcotrione SCHEMBL7587821 0.90 MEN1 (0.49) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7575862 0.89 TDP1 (0.40) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7585981 0.88 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX
Glyphosate SCHEMBL7578037 0.87 MEN1 (0.53) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.