Pretilachlor

Pretilachlor

SCHEMBL7587569

CCCOCCN(C(=O)CCl)c1c(CC)cccc1CC.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.50
FFAR1 O14842 3/20 0.40
MRGPRX4 Q96LA9 7/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TTR P02766 1/20 0.38
PPOX P50336 1/20 0.38
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
CETP P11597 2/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alachlor SCHEMBL7582413 0.89 TP53 (0.46) NR1I2FFAR1MRGPRX4MEN1KMT2A
Acetochlor SCHEMBL7585022 0.87 TDP1 (0.49) FFAR1MRGPRX4MEN1KMT2ATDP1
Lactofen SCHEMBL7578455 0.86 TDP1 (0.48) NR1I2FFAR1MRGPRX4MEN1KMT2A
Dimethachlor SCHEMBL7581929 0.85 FFAR1 (0.42) FFAR1MRGPRX4MEN1KMT2ATDP1
Metolachor SCHEMBL7584513 0.83 FFAR1 (0.39) FFAR1MRGPRX4MEN1KMT2ATDP1
Acifluorfen SCHEMBL7580066 0.82 TDP1 (0.62) NR1I2FFAR1MRGPRX4MEN1KMT2A
Alachlor SCHEMBL7578326 0.81 TP53 (0.39) FFAR1MRGPRX4MEN1KMT2ATDP1
Alachlor SCHEMBL7585632 0.81 TP53 (0.39) FFAR1MRGPRX4MEN1KMT2ATDP1
Alachlor SCHEMBL7587723 0.81 TP53 (0.38) FFAR1MRGPRX4MEN1KMT2ATDP1
SCHEMBL15844933 0.80 FFAR1 (0.56) FFAR1MRGPRX4MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT NR1I2 2507/4885FFAR1 4198/4885MRGPRX4 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.