Primisulfuron

Primisulfuron

SCHEMBL7587641

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
TTR P02766 1/20 0.39
PPOX P50336 1/20 0.39
KMT2A Q03164 1/20 0.39
CDK1 P06493 1/20 0.32
THRB P10828 1/20 0.31
VDR P11473 1/20 0.31
CYP3A4 P08684 1/20 0.30
UGCG Q16739 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7580661 0.94 MEN1 (0.35) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7587423 0.94 TDP1 (0.40) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7580463 0.94 MEN1 (0.34) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7583176 0.93 MEN1 (0.34) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7576988 0.93 TDP1 (0.39) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7590635 0.93 TDP1 (0.46) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7584477 0.92 MEN1 (0.41) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7587599 0.92 MEN1 (0.39) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7588264 0.91 TDP1 (0.47) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7577229 0.90 TDP1 (0.42) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.