Primisulfuron

Primisulfuron

SCHEMBL7587653

COc1c(Cl)ccc(Cl)c1C(=O)O.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O.O=C(O)CNCP(=O)(O)O.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
TTR P02766 1/20 0.43
PPOX P50336 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CCR6 P51684 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
PYGL P06737 1/20 0.31
TBXA2R P21731 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7582749 0.97 MEN1 (0.40) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7575217 0.95 MEN1 (0.41) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7576874 0.95 MEN1 (0.37) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7577680 0.94 TDP1 (0.37) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7586789 0.93 MEN1 (0.37) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7578943 0.93 TDP1 (0.50) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7585876 0.92 MEN1 (0.38) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7578820 0.92 TDP1 (0.42) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7587407 0.91 TDP1 (0.44) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7582151 0.90 MEN1 (0.36) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.