Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707540 | 0.85 | RAB9A (0.69) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL7591224 | 0.80 | KDM4E (0.52) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL11702096 | 0.79 | RAB9A (0.65) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL29510945 | 0.79 | RAB9A (1.00) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL14773948 | 0.79 | RAB9A (1.00) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL7590440 | 0.77 | BRD4 (0.45) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL5089620 | 0.76 | RAB9A (0.70) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL11703407 | 0.76 | RAB9A (0.69) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL11705615 | 0.75 | RAB9A (0.72) | RAB9ANPC1KDM4ENPSR1TDP1 | |
| SCHEMBL17916715 | 0.74 | RAB9A (0.89) | RAB9ANPC1KDM4ENPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |