Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587763 | 0.73 | HTR1D (0.49) | HTR1DHTR1BHTR1A | |
| SCHEMBL8676889 | 0.71 | HTR1A (0.65) | HTR1DHTR1BHTR1ADRD3 | |
| SCHEMBL9189284 | 0.71 | HTR1D (0.46) | HTR1DHTR1BHTR1ADRD3 | |
| SCHEMBL8632679 | 0.71 | HTR1D (0.57) | HTR1DHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL7936160 | 0.70 | HTR1A (0.64) | HTR1DHTR1BHTR1ADRD3 | |
| SCHEMBL7371196 | 0.70 | HTR1D (0.83) | HTR1DHTR1B | |
| SCHEMBL8672825 | 0.69 | HTR1A (0.59) | HTR1DHTR1BHTR1ADRD3 | |
| SCHEMBL8676875 | 0.69 | CHRM2 (0.64) | HTR1DHTR1BHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL7936577 | 0.68 | CHRM2 (0.63) | HTR1DHTR1BHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL7938715 | 0.68 | HTR1A (0.58) | HTR1DHTR1BHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041101-A1 | ENANTIOMERS OF TRANS-BENZ[E]INDOLE COMPOUNDS, THEIR PREPARATION AND UTILITY AS DOPAMINE-D3 RECEPTOR SELECTIVE AGENTS | NOVO NORDISK A/S (DK) | 1997-11-06 | — | — | WO | disclosed |