Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207670 | 1.00 | ADORA2A (0.44) | ADORA2AADORA2BCCNA2CDK2CCNA1 | |
| SCHEMBL7208763 | 0.89 | CCNA2 (0.39) | ADORA2AADORA2BCCNA2CDK2CCNA1 | |
| SCHEMBL7207964 | 0.87 | ADORA2A (0.57) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7587828 | 0.87 | ADORA2A (0.57) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7208637 | 0.85 | ADORA3 (0.57) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7204932 | 0.85 | ADORA2A (0.51) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7104801 | 0.84 | ADORA2A (0.43) | ADORA2AADORA2BCCNA2CDK2CCNA1 | |
| SCHEMBL7151509 | 0.84 | ADORA2A (0.43) | ADORA2AADORA2BCCNA2CDK2CCNA1 | |
| SCHEMBL7208424 | 0.83 | ADORA2A (0.52) | ADORA2AADORA2BCDK2ADORA1 | |
| SCHEMBL7208427 | 0.83 | ADORA2A (0.52) | ADORA2AADORA2BCDK2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |