Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197208 | 0.95 | CYP4F2 (0.56) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL7536168 | 0.86 | SLC7A5 (0.52) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL14415229 | 0.83 | CYP4A11 (0.68) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL31068535 | 0.83 | SLC7A5 (0.58) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL25961093 | 0.83 | SLC7A5 (0.58) | CYP4F2CYP4A11SLC7A5LOXL2 | |
| SCHEMBL29346854 | 0.83 | SLC7A5 (0.58) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL18744852 | 0.82 | SLC7A5 (0.56) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL31688987 | 0.82 | SLC7A5 (0.60) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL19078989 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 | |
| SCHEMBL19078994 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11SLC7A5LOXL2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492550-B2 | INHIBITORS OF THE CYTOSOLIC PHOSPHOLYPASE A2 ENZYMES | BRISTOL-MYERS SQUIBB COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-20020068722-A1 | Alpha-substituted thio,-oxo trifluoromethylketones as phospholipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2002-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068722-A1 | Alpha-substituted thio,-oxo trifluoromethylketones as phospholipase inhibitors | PLA2G4B, PLA2G4A, PLA2G1B | CYP4F2 275/4885CYP4A11 689/4885SLC7A5 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.