Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587968 | 0.86 | CYP4F2 (0.56) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL4197208 | 0.84 | CYP4F2 (0.56) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL18045902 | 0.83 | CYP4F2 (0.62) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL29346854 | 0.82 | SLC7A5 (0.58) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL30873957 | 0.82 | SLC7A5 (0.61) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL31068535 | 0.82 | SLC7A5 (0.58) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL5382573 | 0.79 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11LOXL2ALDH1A1 | |
| SCHEMBL7505386 | 0.79 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2MRGPRX4 | |
| SCHEMBL31487557 | 0.79 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2MRGPRX4 | |
| SCHEMBL7504785 | 0.78 | SLC7A5 (0.63) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414179-B1 | USEFUL AGENTS IN THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS ASTHMA, ARTHRITIS, INFLAMMATORY BOWEL DISEASE AND NEURODEGENERATIVE DISEASES | BRISTOL-MYERS SQUIBB COMPANY | 2002-07-02 | — | — | US | disclosed |
| US-20020065246-A1 | Alpha-and beta- substituted trifluoromethyl ketones as phospholipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2002-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065246-A1 | Alpha-and beta- substituted trifluoromethyl ketones as phospholipase inhibitors | PLA2G4B, PLA2G1B, PLA2R1 | SLC7A5 4571/4885CYP4F2 991/4885CYP4A11 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.