Logran

Logran

SCHEMBL7587995

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorsulfuron SCHEMBL7589400 0.94 KDM4E (0.34) KDM4EMEN1HSP90AA1MAPTKMT2A
SCHEMBL7585257 0.93 KDM4E (0.32) KDM4EMEN1HSP90AA1MAPTKMT2A
Logran SCHEMBL7576657 0.92 KDM4E (0.34) KDM4EMEN1MAPTKMT2A
Lactofen SCHEMBL7587475 0.90 MEN1 (0.35) MEN1MAPTKMT2ANPSR1L3MBTL1
SCHEMBL7578244 0.89 KDM4E (0.31) KDM4EMEN1HSP90AA1MAPTKMT2A
Iodosulfuron SCHEMBL7584927 0.89 KDM4E (0.31) KDM4EMEN1HSP90AA1MAPTKMT2A
Logran SCHEMBL7588379 0.88 KMT2A (0.43) KDM4EMEN1HSP90AA1MAPTKMT2A
Fomesafen SCHEMBL7577289 0.87 MEN1 (0.37) KDM4EMEN1HSP90AA1MAPTKMT2A
Logran SCHEMBL7589517 0.86 MEN1 (0.36) KDM4EMEN1HSP90AA1MAPTKMT2A
Logran SCHEMBL7589682 0.86 KMT2A (0.34) KDM4EMEN1HSP90AA1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KDM4E 1886/4885MEN1 4274/4885HSP90AA1 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.