Nicosulfuron

Nicosulfuron

SCHEMBL7588031

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.CP(=O)(O)CCC(N)C(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
GRM8 O00222 11/20 0.35
GRM4 Q14833 11/20 0.35
GRM6 O15303 6/20 0.35
PPARG P37231 1/20 0.33
CDK1 P06493 1/20 0.33
GRM7 Q14831 2/20 0.32
JMJD7 P0C870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7585418 0.93 TDP1 (0.38) TDP1GRM8GRM4GRM6CDK1
Nicosulfuron SCHEMBL7584989 0.93 TDP1 (0.38) TDP1GRM8GRM4GRM6
Rimsulfuron SCHEMBL7582269 0.91 TDP1 (0.44) TDP1GRM8GRM4GRM6PPARG
Nicosulfuron SCHEMBL7582294 0.90 TDP1 (0.54) TDP1PPARGCDK1JMJD7
Nicosulfuron SCHEMBL7580459 0.90 TDP1 (0.44) TDP1GRM8GRM4GRM6CDK1
Nicosulfuron SCHEMBL7577305 0.89 TDP1 (0.34) TDP1
Nicosulfuron SCHEMBL7589102 0.89 TDP1 (0.39) TDP1GRM8GRM4GRM6CDK1
Nicosulfuron SCHEMBL7577839 0.88 TDP1 (0.45) TDP1PPARGCDK1JMJD7
Nicosulfuron SCHEMBL7588072 0.88 TDP1 (0.36) TDP1GRM8GRM4GRM6
Lactofen SCHEMBL7586782 0.87 TDP1 (0.36) TDP1GRM8GRM4GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885GRM8 3918/4885GRM4 3673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.