Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083304 | 0.77 | NPSR1 (0.41) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6057160 | 0.76 | NPSR1 (0.43) | NPSR1MAPK1TSHRHTTKMT2A | |
| SCHEMBL7259960 | 0.76 | L3MBTL1 (0.47) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22889934 | 0.75 | NPSR1 (0.39) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9939724 | 0.75 | NPSR1 (0.39) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22116876 | 0.75 | KDM4E (0.47) | NPSR1L3MBTL1KDM4EALDH1A1HIF1A | |
| SCHEMBL31500546 | 0.74 | NPSR1 (0.47) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7452572 | 0.74 | NPSR1 (0.47) | NPSR1MAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10314919 | 0.74 | NPSR1 (0.42) | NPSR1MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL26910332 | 0.74 | NPSR1 (0.42) | NPSR1MAPK1KDM4EALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248867-A1 | SELECTIVE ELECTROCHEMICAL REDUCTION OF HALOGENATED 4-AMINOPICOLINIC ACIDS | Dow AgroSciences LLC (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001051684-A1 | SELECTIVE ELECTROCHEMICAL REDUCTION OF HALOGENATED 4-AMINOPICOLINIC ACIDS | DOW AGROSCIENCES, LLC (US) | 2001-07-19 | — | — | WO | disclosed |