SCHEMBL7588460

SCHEMBL7588460

Nc1ncnc2c1ncn2[C@@H]1C=C[C@@H](CO)C(O)C1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADCY5 O95622 13/20 0.60
AHCY P23526 3/20 0.57
ADORA2B P29275 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894877 1.00 ADCY5 (0.60) ADCY5AHCYADORA2B
SCHEMBL4898499 1.00 ADCY5 (0.60) ADCY5AHCYADORA2B
SCHEMBL5997273 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL12157255 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL5998483 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL5997270 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL111590 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL30969131 0.84 ADCY5 (0.74) ADCY5AHCYADORA2B
SCHEMBL9147328 0.82 ADCY5 (0.64) ADCY5AHCY
SCHEMBL8660508 0.82 ADCY5 (0.64) ADCY5AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210347-A1 CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH Stichting REGA V.Z.W. (BE) 2002-06-05 EP disclosed
WO-2001018003-A1 CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH STICHTING REGA VZW (BE) 2001-03-15 WO disclosed