Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592919 | 0.94 | LMNA (0.37) | LMNAPOLBMAPTITGB3ITGA2B | |
| SCHEMBL7795621 | 0.90 | LMNA (0.39) | LMNAPOLBMAPTITGB3ITGA2B | |
| SCHEMBL7796040 | 0.83 | ITGB3 (0.40) | LMNAPOLBMAPTITGB3ITGA2B | |
| SCHEMBL7796055 | 0.78 | ITGB1 (0.41) | LMNAMAPTITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7796051 | 0.77 | MAPK1 (0.43) | LMNAPOLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7795113 | 0.77 | ITGB3 (0.55) | POLBITGB3ITGA2BITGAV | |
| SCHEMBL7795627 | 0.73 | SMN1; SMN2 (0.39) | MAPTITGB3ITGA2BSMN1; SMN2KDM4E | |
| SCHEMBL7796029 | 0.73 | NPC1 (0.39) | LMNAPOLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7796035 | 0.72 | MAPT (0.40) | LMNAPOLBMAPTITGB3ITGA2B | |
| SCHEMBL8180024 | 0.71 | ITGB3 (0.44) | MAPTITGB3ITGA2BHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |