Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297010 | 1.00 | THRB (0.42) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL28360471 | 0.97 | THRB (0.39) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL31253489 | 0.90 | THRB (0.35) | THRB | |
| SCHEMBL718350 | 0.82 | THRB (0.44) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL717932 | 0.82 | THRB (0.44) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL4401769 | 0.79 | THRB (0.38) | THRB | |
| SCHEMBL7712281 | 0.79 | THRB (0.38) | THRB | |
| SCHEMBL4400459 | 0.79 | THRB (0.38) | THRB | |
| SCHEMBL4390006 | 0.79 | THRB (0.38) | THRB | |
| SCHEMBL29267902 | 0.79 | THRB (0.40) | THRBCA2CA1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889718-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-09-18 | — | — | EP | disclosed |