Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717932 | 1.00 | THRB (0.44) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL29267902 | 0.97 | THRB (0.40) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL7986043 | 0.89 | THRB (0.36) | THRB | |
| SCHEMBL892719 | 0.83 | F2 (0.35) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL29841696 | 0.83 | THRB (0.35) | THRBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL3297010 | 0.82 | THRB (0.42) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL7589040 | 0.82 | THRB (0.42) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL3958320 | 0.81 | THRB (0.40) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL9116861 | 0.80 | THRB (0.41) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL9137488 | 0.80 | THRB (0.41) | THRBCA2CA1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316822-B1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2016-10-26 | — | — | EP | claimed |
| EP-2407449-B1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2015-01-07 | — | — | EP | claimed |
| US-8765993-B2 | One-pot production of carbamates using solid catalysts | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-07-01 | — | — | US | claimed |
| US-8735621-B2 | Preparation of carbamates with solid catalysts | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-05-27 | — | — | US | claimed |
| US-20120053359-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | UNIVERSIDAD POLITECNICA DE VALENCIA (ES) | 2012-03-01 | — | — | US | claimed |
| EP-2407449-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2012-01-18 | — | — | EP | claimed |
| US-20110124902-A1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | Consejo Superior De Investigaciones Cientificas C/Serrano, 117 (ES) | 2011-05-26 | — | — | US | claimed |
| EP-2316822-A1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | Consejo Superior De Investigaciones Científicas (ES) | 2011-05-04 | — | — | EP | claimed |
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | claimed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | claimed |
| EP-2316822-B1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2016-10-26 | — | — | EP | disclosed |
| EP-2407449-B1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2015-01-07 | — | — | EP | disclosed |
| US-8765993-B2 | One-pot production of carbamates using solid catalysts | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-07-01 | — | — | US | disclosed |
| US-8735621-B2 | Preparation of carbamates with solid catalysts | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-05-27 | — | — | US | disclosed |
| US-20120053359-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | UNIVERSIDAD POLITECNICA DE VALENCIA (ES) | 2012-03-01 | — | — | US | disclosed |
| EP-2407449-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2012-01-18 | — | — | EP | disclosed |
| US-20110124902-A1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | Consejo Superior De Investigaciones Cientificas C/Serrano, 117 (ES) | 2011-05-26 | — | — | US | disclosed |
| EP-2316822-A1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | Consejo Superior De Investigaciones Científicas (ES) | 2011-05-04 | — | — | EP | disclosed |
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053359-A1 | ONE-POT PRODUCTION OF CARBAMATES USING SOLID CATALYSTS | CA7, CA2, CA4 | THRB 4494/4885CA2 2/4885CA1 6/4885 |
| US-20110124902-A1 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS | ODC1, RCC1, OTC | THRB 4825/4885CA2 5/4885CA1 18/4885 |
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | SRM, CA4, PRMT3 | THRB 4475/4885CA2 10/4885CA1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.