Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592553 | 0.88 | LMNA (0.57) | LMNACYP2C19HIF1A | |
| SCHEMBL5162293 | 0.86 | LMNA (0.47) | LMNACYP2C19HIF1A | |
| SCHEMBL7590181 | 0.85 | LMNA (0.49) | LMNACYP2C19HIF1A | |
| SCHEMBL7594716 | 0.83 | LMNA (0.37) | LMNACYP2C19HIF1A | |
| SCHEMBL10318442 | 0.83 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL13247559 | 0.83 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL12957694 | 0.83 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL7590959 | 0.83 | LMNA (0.34) | LMNA | |
| SCHEMBL10455518 | 0.82 | LMNA (0.61) | LMNACYP2C19HIF1A | |
| SCHEMBL3752378 | 0.81 | LMNA (0.63) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |