SCHEMBL5162293

SCHEMBL5162293

NC(=O)c1c(I)c(NC(=O)CO)c(I)c(C(=O)N(CC(O)CO)CC(O)CO)c1I

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10318442 0.96 LMNA (0.44) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL9191001 0.93 LMNA (0.44) LMNACYP2C19HIF1A
SCHEMBL7607980 0.92 LMNA (0.47) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL5033195 0.90 LMNA (0.45) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL8663593 0.88 LMNA (0.61) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL1048643 0.87 LMNA (0.44) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL13247559 0.86 LMNA (0.60) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL7589084 0.86 LMNA (0.43) LMNACYP2C19HIF1A
SCHEMBL10455518 0.85 LMNA (0.61) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL9171058 0.85 LMNA (0.53) LMNACYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008104853-A1 PROCESSES FOR THE PREPARATION OF PURE IOVERSOL WOCKHARDT RESEARCH CENTRE (IN) 2008-09-04 WO claimed