Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626581 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL17164467 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL7969600 | 0.78 | ALDH1A1 (0.51) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL19245074 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL18631638 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL18631637 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL10503384 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1TDP1LMNAALOX5MAPT | |
| SCHEMBL7636892 | 0.75 | ALDH1A1 (0.49) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 | |
| SCHEMBL8741502 | 0.75 | HDAC2 (0.51) | ALDH1A1MAPK1KMT2ATSHRLMNA | |
| SCHEMBL24859301 | 0.75 | ALDH1A1 (0.61) | ALDH1A1ELANEL3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| EP-0573289-B1 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INT BV (NL) | 1999-04-28 | — | — | EP | disclosed |
| US-5628980-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-05-13 | — | — | US | disclosed |
| US-5614638-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-03-25 | — | — | US | disclosed |
| US-5591846-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. | 1997-01-07 | — | — | US | disclosed |
| US-5559237-A | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1996-09-24 | — | — | US | disclosed |
| US-5359077-A | Process for preparation of 2-oxo-1 piperidinyl derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0573289-A2 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1993-12-08 | — | — | EP | disclosed |