Acifluorfen

Acifluorfen

SCHEMBL7589115

CC(C)N1C(=O)c2ccccc2NS1(=O)=O.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.63
MEN1 O00255 1/20 0.63
TTR P02766 1/20 0.63
PPOX P50336 1/20 0.63
KMT2A Q03164 1/20 0.63
KDM4E B2RXH2 1/20 0.43
RECQL P46063 1/20 0.43
MASP2 O00187 1/20 0.38
F2 P00734 1/20 0.38
FFAR1 O14842 3/20 0.38
AKR1B1 P15121 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
PYGL P06737 1/20 0.37
LMNA P02545 3/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
CCR6 P51684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL22581771 0.94 TDP1 (0.53) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7586731 0.89 TDP1 (0.49) TDP1MEN1TTRPPOXKMT2A
Bentazon SCHEMBL7581665 0.88 MEN1 (0.48) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7587636 0.87 MEN1 (0.44) TDP1MEN1TTRPPOXKMT2A
Bentazon SCHEMBL7583707 0.85 KDM4E (0.45) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7582299 0.83 MEN1 (0.42) TDP1MEN1TTRPPOXKMT2A
Bentazon SCHEMBL7582336 0.82 MEN1 (0.42) TDP1MEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7581632 0.82 TDP1 (0.42) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7575036 0.82 MEN1 (0.41) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7589480 0.82 TDP1 (0.41) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.