Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041959 | 0.86 | REN (0.49) | RENMET | |
| SCHEMBL6042547 | 0.84 | REN (0.45) | RENMET | |
| SCHEMBL6043292 | 0.82 | REN (0.47) | RENGRIN2B | |
| SCHEMBL6041854 | 0.82 | REN (0.47) | REN | |
| SCHEMBL6042834 | 0.81 | REN (0.43) | REN | |
| SCHEMBL6041921 | 0.80 | REN (0.70) | REN | |
| SCHEMBL6041356 | 0.80 | REN (0.42) | RENMET | |
| SCHEMBL6043637 | 0.79 | REN (0.41) | RENMET | |
| SCHEMBL7079701 | 0.78 | REN (0.41) | RENMET | |
| SCHEMBL7564655 | 0.77 | REN (0.42) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |