Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 7/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570846 | 0.81 | SLC22A12 (0.62) | SLC40A1ALPLSLC22A12WDR5 | |
| SCHEMBL22315142 | 0.72 | SLC22A12 (0.59) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL22252121 | 0.72 | ALPL (0.61) | SLC40A1ALPLBRD4WDR5IDH1 | |
| SCHEMBL10154346 | 0.72 | ALPL (0.52) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL21513749 | 0.72 | ALPL (0.46) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL29968601 | 0.72 | ALPL (0.46) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL26074505 | 0.72 | MRGPRX1 (0.53) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL6735794 | 0.71 | ALPL (0.51) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL27999788 | 0.71 | ALPL (0.53) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 | |
| SCHEMBL31305132 | 0.71 | SLC22A12 (0.48) | SLC40A1ALPLSLC22A12BRD4MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |