Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.62 |
| ▸ | ALPL | P05186 | 9/20 | 0.60 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589183 | 0.81 | SLC40A1 (0.51) | SLC22A12ALPLSLC40A1WDR5 | |
| SCHEMBL95622 | 0.79 | ALPL (0.58) | SLC22A12ALPLSLC40A1GSPT1DDB1 | |
| SCHEMBL31305232 | 0.77 | SLC22A12 (0.50) | SLC22A12ALPLWDR5HSD17B1HSD17B2 | |
| SCHEMBL27999788 | 0.76 | ALPL (0.53) | SLC22A12ALPLSLC40A1GSPT1DDB1 | |
| SCHEMBL31305098 | 0.75 | FABP4 (0.49) | SLC22A12ALPLWDR5HSD17B1HSD17B2 | |
| SCHEMBL2158362 | 0.75 | ALPL (0.54) | SLC22A12ALPLSLC40A1GSPT1DDB1 | |
| SCHEMBL10154346 | 0.74 | ALPL (0.52) | SLC22A12ALPLSLC40A1 | |
| SCHEMBL418590 | 0.74 | ALPL (0.52) | SLC22A12ALPLSLC40A1GSPT1DDB1 | |
| SCHEMBL28312855 | 0.74 | SLC22A12 (0.54) | SLC22A12ALPLSLC40A1GSPT1DDB1 | |
| SCHEMBL8229520 | 0.74 | ALPL (0.52) | SLC22A12ALPLSLC40A1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |