Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595680 | 0.91 | CYP2C19 (0.38) | CYP2C19HIF1ALMNA | |
| SCHEMBL7594419 | 0.83 | LMNA (0.31) | CYP2C19HIF1ALMNA | |
| SCHEMBL7591094 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL7590516 | 0.80 | LMNA (0.39) | LMNA | |
| SCHEMBL7595662 | 0.76 | LMNA (0.43) | CYP2C19HIF1ALMNA | |
| SCHEMBL7591003 | 0.75 | — | — | |
| SCHEMBL7589733 | 0.70 | LMNA (0.38) | LMNA | |
| SCHEMBL10591568 | 0.69 | CYP2C19 (0.59) | CYP2C19HIF1ALMNA | |
| SCHEMBL7589285 | 0.68 | LMNA (0.41) | LMNA | |
| SCHEMBL7593927 | 0.68 | CYP2C19 (0.39) | CYP2C19HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |