SCHEMBL7589733

SCHEMBL7589733

O=C(Nc1c(I)c(CC(O)CO)c(I)c(NC(=O)C(O)CO)c1I)C(O)CO

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589285 0.85 LMNA (0.41) LMNASMN1; SMN2
SCHEMBL7594419 0.82 LMNA (0.31) LMNA
SCHEMBL7595489 0.82 LMNA (0.34) LMNASMN1; SMN2
SCHEMBL28584676 0.82 LMNA (0.33) LMNASMN1; SMN2
SCHEMBL7590516 0.82 LMNA (0.39) LMNASMN1; SMN2
SCHEMBL7589638 0.75 LMNA (0.33) LMNASMN1; SMN2
SCHEMBL6226822 0.74 LMNA (0.46) LMNASMN1; SMN2
SCHEMBL27932819 0.73 TYMP (0.32)
SCHEMBL9563831 0.73 LMNA (0.53) LMNASMN1; SMN2
SCHEMBL8517379 0.73 LMNA (0.47) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US claimed
US-6448442-B1 X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS AMERSHAM HEALTH AS (NO) 2002-09-10 US disclosed
US-6310243-B1 BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY NYCOMED IMAGING AS (NO) 2001-10-30 US disclosed
WO-2000037115-A1 WATER-SOLUBLE CONTRAST MEDIA FOR X-RAY IMAGING NYCOMED IMAGING AS (NO) 2000-06-29 WO disclosed
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US disclosed