Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.65 |
| ▸ | CTSL | P07711 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850124 | 0.80 | CTSV (0.79) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL354532 | 0.80 | CTSV (1.00) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL2855116 | 0.79 | KMT2A (0.50) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL22720188 | 0.79 | MAPT (0.74) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL11337250 | 0.77 | MAPT (0.68) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL3025510 | 0.77 | MAPT (0.67) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL7593343 | 0.76 | KMT2A (0.57) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3020359 | 0.76 | MAPT (0.79) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL2441231 | 0.76 | LMNA (0.59) | MAPTKMT2AALDH1A1GAAMAPK1 | |
| SCHEMBL3032132 | 0.74 | MAPT (0.71) | CTSVCTSLMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780376-B1 | 2-Acylamino-9-aryl-acridines, process for their preparation, and light-sensitive compositions containing them | AGFA GEVAERT (BE) | 2002-10-16 | — | — | EP | disclosed |
| US-5834157-A | PHOTOINITIATORS; REDUCED DIFFUSION AND SUBLIMATION | AGFA-GEVAERT AG (DE) | 1998-11-10 | — | — | US | disclosed |
| EP-0780376-A1 | 2-Acylamino-9-aryl-acridines, process for their preparation and light-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-25 | — | — | EP | disclosed |