SCHEMBL7589484

SCHEMBL7589484

N#C/C=C/C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589489 1.00 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL99074 0.75
SCHEMBL1013554 0.75
SCHEMBL99073 0.75
SCHEMBL17356122 0.71
SCHEMBL31110311 0.69
SCHEMBL333596 0.69
SCHEMBL31110310 0.69
SCHEMBL333597 0.69
SCHEMBL2465905 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663394-B1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL CO (JP) 2002-11-13 EP disclosed
US-5498725-A Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0663394-A1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-07-19 EP disclosed