Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 4/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688103 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL688530 | 0.94 | CTSA (0.43) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL687651 | 0.94 | CTSA (0.44) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL27762471 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL687232 | 0.89 | CTSA (0.46) | ALDH1A1KDM4EMAPK1CTSAPOLB | |
| SCHEMBL687960 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL688172 | 0.88 | MAPT (0.41) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL688529 | 0.87 | CTSA (0.39) | MEN1KMT2ACTSAPOLB | |
| SCHEMBL687681 | 0.86 | CTSA (0.42) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL688117 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000067746-A9 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2002-08-29 | — | — | WO | claimed |