SCHEMBL7589580

SCHEMBL7589580

C#CCOc1cc(-n2nc3n(c2=O)CCCC3)c(Cl)cc1Cl.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 17/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorsulfuron SCHEMBL7587554 0.95 DHODH (0.42) DHODH
Iodosulfuron SCHEMBL7581283 0.93 DHODH (0.39) DHODH
SCHEMBL7590341 0.91 DHODH (0.35) DHODH
Logran SCHEMBL7577354 0.91 DHODH (0.39) DHODH
SCHEMBL7585005 0.90 DHODH (0.38) DHODH
SCHEMBL7581193 0.90 DHODH (0.39) DHODH
SCHEMBL7580435 0.89 KDM4E (0.42) DHODH
Primisulfuron SCHEMBL7579226 0.89 DHODH (0.39) DHODH
Prosulfuron SCHEMBL7589704 0.89 DHODH (0.41) DHODH
Thifensulfuron-Methyl SCHEMBL7583625 0.87 DHODH (0.38) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT DHODH 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.