Flazasulfuron

Flazasulfuron

SCHEMBL7589776

C#CCOc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
NR1I2 O75469 1/20 0.33
PKM P14618 1/20 0.31
KDR P35968 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL7582625 0.92 PPOX (0.43) PPOXMEN1KMT2ATDP1NR1I2
Flupyrsulfuron SCHEMBL7581742 0.92 PPOX (0.31) PPOXMEN1KMT2ATDP1NR1I2
Flazasulfuron SCHEMBL7579255 0.91 PPOX (0.39) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL7590754 0.90 PPOX (0.34) PPOXMEN1KMT2ATDP1NR1I2
Flazasulfuron SCHEMBL7580180 0.87 DHODH (0.38)
Sulfosulfuron SCHEMBL7576715 0.87 MEN1 (0.30) PPOXMEN1KMT2ATDP1NR1I2
Chlorsulfuron SCHEMBL7590420 0.86 KDM4E (0.34) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL7588208 0.84 PPOX (0.32) PPOXMEN1KMT2ATDP1NR1I2
Flupyrsulfuron SCHEMBL7580775 0.84 MEN1 (0.41) PPOXMEN1KMT2ATDP1NR1I2
Rimsulfuron SCHEMBL7575812 0.83 PPOX (0.39) PPOXMEN1KMT2ATDP1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.