Sugi Predict

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Bifenox

Bifenox

SCHEMBL7589822

CCNc1nc(Cl)nc(NCC)n1.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.57
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ TTR P02766 1/20 0.37
▸ PPOX P50336 1/20 0.37
▸ MAPT P10636 6/20 0.35
▸ PKM P14618 1/20 0.34
▸ LMNA P02545 3/20 0.34
▸ GAA P10253 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ HIF1A Q16665 1/20 0.33
▸ FFAR1 O14842 2/20 0.33
▸ PLA2G1B P04054 1/20 0.32
▸ ATG4B Q9Y4P1 1/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7588627 0.96 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7589277 0.96 TDP1 (0.52) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7575612 0.93 TDP1 (0.60) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7582885 0.93 TDP1 (0.49) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7581849 0.91 TDP1 (0.69) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7582232 0.89 TDP1 (0.55) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7587559 0.89 TDP1 (0.55) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7584350 0.87 TDP1 (0.75) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7583154 0.86 TDP1 (0.57) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7576725 0.86 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.