Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 2/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942676 | 0.86 | RAB9A (0.52) | LMNAALDH1A1CYP2C9HSD17B10L3MBTL1 | |
| SCHEMBL229404 | 0.76 | HDAC1 (0.53) | LMNAALDH1A1CDC7DBF4ABL1 | |
| Hydrochloric Acid SCHEMBL5155818 | 0.75 | HDAC1 (0.52) | LMNAALDH1A1CDC7DBF4ABL1 | |
| SCHEMBL12144898 | 0.73 | CDC7 (0.50) | LMNACDC7DBF4DAOKDM6B | |
| SCHEMBL942486 | 0.73 | NPC1 (0.45) | LMNAALDH1A1HSD17B10DAOTAAR1 | |
| SCHEMBL12144894 | 0.73 | DAO (0.45) | LMNAALDH1A1CDC7DBF4MEN1 | |
| SCHEMBL8539114 | 0.72 | MTOR (0.46) | ALDH1A1CYP2C9CDC7DBF4MEN1 | |
| SCHEMBL7618263 | 0.71 | TAAR1 (0.58) | LMNAALDH1A1CYP2C9KMT2AHSD17B10 | |
| SCHEMBL8883167 | 0.71 | ALDH1A1 (0.59) | ALDH1A1CYP2C9CDC7DBF4MEN1 | |
| SCHEMBL12144892 | 0.71 | DAO (0.39) | ALDH1A1CDC7DBF4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109259-A1 | PYRAZINONE DERIVATIVES AS INSULIN SECRETION STIMULATORS, METHODS FOR OBTAINING THEM AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2009-09-11 | — | — | WO | disclosed |
| US-6413911-B1 | REACTING A SULFONYL ISOCYANATE WITH A 2-AMINO-1,3,5-TRIAZINE OR 2-AMINOPYRIMIDINE, OR REACTING A SULFONAMIDE WITH A PHENYL CARBAMATE OR ISOCYANATE OF -1,3,5-TRIAZINE OR PYRIDINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | MAYER HORST (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6320046-B1 | A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-20 | — | — | US | disclosed |
| EP-0666708-B1 | HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES | FMC CORP (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6043196-A | Herbicidal sulfonylureas, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0666708-A4 | HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES. | — | 1995-08-23 | — | — | EP | disclosed |
| EP-0666708-A1 | HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES | FMC CORPORATION (US) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994009629-A1 | HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES | FMC CORPORATION (US) | 1994-05-11 | — | — | WO | disclosed |
| US-5208212-A | Synergistic | FMC CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | SLC5A1, DDT, SLC5A2 | LMNA 3715/4885ALDH1A1 1171/4885CYP2C9 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.